Showing posts sorted by relevance for query NMR Spectroscopy. Sort by date Show all posts
Showing posts sorted by relevance for query NMR Spectroscopy. Sort by date Show all posts

Oct 1, 2023

Exploring the Diverse Applications of Spectroscopy: From Chemistry to Medicine and Beyond

In this blog, we will delve into the diverse applications of spectroscopy, showcasing its significance in chemistry, medicine, environmental science, and beyond.

Spectroscopy, the study of the interaction between matter and electromagnetic radiation, has evolved into a powerful scientific tool with applications spanning various fields. 

Keywords: Spectroscopy, Electromagnetic radiationDiagnosis, Technology.

Aug 26, 2021

How to Calculate Coupling Constant (J values) in Proton NMR Spectroscopy

Hi Friends, in this article we will see how to calculate coupling constants (J values) in 1H-NMR Spectroscopy.

Key wordsCoupling constant, Multiplicity1H-NMR spectrum, Signal.

Definition of coupling constant

The coupling constant is a distance between sub-peaks expressed in hertz. In 1H-NMR spectrum a peak splits into multiple sub-peaks due to coupling with neighboring protons. The value of coupling constant does not depend upon frequency of machine and solvent used for NMR experiment.

We have discussed various applications of spectroscopy in chemistry, medicine and environmental science in another article. Please check out for more details. [Link]

Jun 29, 2023

Resonance Effect Simplified: A Comprehensive Guide for Chemists

Chemistry is a vast field with numerous concepts and phenomena to explore. Among these, the resonance effect holds significant importance, especially in organic chemistry. Understanding the resonance effect is crucial for chemists as it helps explain the stability and reactivity of various organic compounds. 

In this article, we will learn fundamentals of the resonance effect, its applications, and its role in chemical reactions.

Jul 9, 2023

Exploring the Inductive Effect in Chemistry: Applications and Implications

In the vast field of organic chemistry, understanding the various factors that influence the behavior of organic compounds is of principal importance. One such influential factor is the inductive effect. The inductive effect is a fundamental concept that plays a crucial role in determining the reactivity, stability, and physical properties of organic molecules. In this article, we will explore the significance of the inductive effect and its implications in organic chemistry.

Jun 13, 2022

Multiplicity of peak in 1H-NMR spectroscopy

Multiplicity of peak in 1H-NMR spectrum is splitting of one peak in to two or many peaks.

Hi Friends, in this article we will learn about splitting and multiplicity of peak in 1H-NMR. In previous article we have seen that how we can find coupling constant or J-value of the peak in 1H-NMR spectrum.[Link]

We have discussed various applications of spectroscopy in chemistry, medicine and environmental science in another article. Please check out for more details. [Link]

Jan 19, 2024

Exploring Rotamers and Their Significance in Science and Drug Discovery

Rotamers, the dynamic conformations that molecules adopt, play a crucial role in the world of molecular biology and chemistry. This intricate dance of atoms significantly impacts the properties and functions of molecules. In this blog, we will delve into the fascinating realm of rotamers, shedding light on their importance in science and drug Discovery.

Table of Contents

  1. What are Rotamers?
  2. The Importance of Rotamers
  3. How to Study Rotamers
  4. Exploring Rotamer Dynamics
  5. Conclusion

Dec 15, 2024

Identification, Characterization, Synthesis, and Isolation of API Impurities: A Comprehensive Guide

In the pharmaceutical industry, the purity of Active Pharmaceutical Ingredients (APIs) is crucial for ensuring safety, efficacy, and regulatory compliance. The presence of impurities can impact the quality of the final product, making their identification, characterization, synthesis, and isolation vital steps in the drug development process. In this blog, we’ll explore these essential aspects and their importance in pharmaceutical development.

Key wordsActive Pharmaceutical Ingredients (APIs)Drug Master File (DMF)API Impurities.

Oct 7, 2023

Exploring the Wide-ranging Applications of Mass Spectrometry

In this article we will discuss about significance and application of mass spectrometry in science and industry. 

In the ever-evolving landscape of science and industry, cutting-edge technologies play a pivotal role in driving innovation and discovery. Among these, mass spectrometry stands out as a powerful analytical technique that has revolutionized various fields, ranging from chemistry and biology to environmental science and beyond. Let's delve into the diverse applications of mass spectrometry, showcasing its profound impact on scientific research and industrial processes.

KeywordsMass SpectrometryGas chromatography (GC), Liquid chromatography (LC)High-resolution liquid chromatography (HPLC)

Jul 29, 2023

Mesomeric Effect: Understanding its Significance in Organic Chemistry

The mesomeric effect, also known as resonance effect or conjugation effect, is a fundamental concept in organic chemistry. It plays a crucial role in understanding the behavior and reactivity of organic compounds. This article aims to provide a comprehensive overview of the mesomeric effect, its implications, and its significance in the field of organic chemistry.

Sep 20, 2021

Laboratory Techniques in Organic Chemistry

Laboratory Techniques in Organic Chemistry are some methods used to execute an experiment in lab. In organic chemistry lab various reactions or functional group transformations are performed by using numerous chemicals and instruments. 

May 13, 2023

Rf Value: Calculation, Significance and Affecting Factors

In this article we will learn about Rf value also known as Retention Factor. Here we will discuss calculation of Rf values and its importance in thin layer chromatography.  

Key wordsRf value or Retention factor, Thin layer chromatography (TLC), stationary phase, mobile phase. 

Jan 12, 2024

Exploring the Diverse Applications of HPLC

High-Performance Liquid Chromatography (HPLC) stands at the forefront of analytical techniques, playing a pivotal role in various industries. From pharmaceuticals to environmental analysis, HPLC's versatility makes it an indispensable tool for scientists and researchers. In this article, we delve into the diverse applications of HPLC, exploring its impact on drug development, environmental safety, food quality, clinical research, and beyond. 

Key words High-performance liquid chromatography (HPLC), analytical technique, separation techniques, 

Feb 18, 2021

How to Calculate Index of Hydrogen Deficiency (IHD) or Degree of Unsaturation

Degree of unsaturation also known as Index of hydrogen deficiency (IHD) is number of pi bond or ring present in the structure of organic molecule. This value helps to elucidate structure of unknown molecules. 

Key words: Molecular formula, Index of hydrogen deficiency (IHD), Structure analysis.

In this article we will learn about calculation of degree of unsaturation in organic chemistry.

Mar 25, 2025

Top 10 Organic Chemistry Concepts Every Graduate Student Must Master

Organic chemistry is a vast and complex field, forming the foundation for many scientific disciplines, including pharmaceuticals, biochemistry, and materials science. For graduate students, mastering key concepts in organic chemistry is essential for success in research and academia. Here are the top 10 organic chemistry concepts every graduate student must understand. (Figure 1)

Organic Chemistry Concepts
Fig 1: Organic Chemistry Concepts

Aug 10, 2021

Purification of Organic Compounds

Purification of organic compounds can be accomplished using a variety of approaches. There are techniques or methods used by organic chemists to purify chemical compounds in laboratory. 

Key words: Purification, Organic compounds, Chromatography, Crystallization.