Showing posts with label Stereochemistry. Show all posts
Showing posts with label Stereochemistry. Show all posts

Jan 19, 2024

Exploring Rotamers and Their Significance in Science and Drug Discovery

Rotamers, the dynamic conformations that molecules adopt, play a crucial role in the world of molecular biology and chemistry. This intricate dance of atoms significantly impacts the properties and functions of molecules. In this blog, we will delve into the fascinating realm of rotamers, shedding light on their importance in science and drug Discovery.

Table of Contents

  1. What are Rotamers?
  2. The Importance of Rotamers
  3. How to Study Rotamers
  4. Exploring Rotamer Dynamics
  5. Conclusion

Dec 3, 2023

Understanding the Mysteries of Mutarotation: A Comprehensive Guide

In this blog we will learn about mutarotation. To understand the concept, it is important to understand related terminologies like Isomers, chirality, anomeric effect, and anomeric carbon. We have discussed these concepts in separate articles. Links are given below in reference section as well. 

Key words: Mutarotation, Anomeric carbon, Anomeric effect, and Chirality.

Sep 25, 2023

Unlocking the Anomeric Effect: A Comprehensive Guide to Its Chemistry and Significance

In this comprehensive guide, we will delve deep into the chemistry and significance of the Anomeric Effect, shedding light on factors which are responsible for Anomeric Effect. 

Sep 16, 2023

Understanding Epimers in Organic Chemistry: Key Concepts and Examples

Are you curious about epimers in organic chemistry and want to delve deeper into this fascinating topic? You're in the right place! Epimers are crucial compounds in organic chemistry, and a solid understanding of their key concepts and examples can significantly enhance your grasp of the subject. In this blog post, we'll unravel the mysteries of epimers, explore their significance, and provide you with real-life examples to make learning this concept a breeze.

Jul 29, 2023

Understanding Steric Effects: Impact on Molecular Structure and Reactivity

In the realm of organic chemistry, the study of molecules extends beyond their chemical bonds and electronic properties. The three-dimensional arrangement of atoms within a molecule plays a significant role in determining its behavior and reactivity. This spatial consideration is known as "steric effects." In this blog, we will explore the concept of steric effects, its implications, and its importance in the world of chemistry.

May 6, 2023

Stereoselectivity - Definition, Significance and Examples

In this article we will learn about stereoselectivity. Here we will discuss significance of stereoselective reactions with examples.  

Key words :StereochemistryStereoselective Reaction, Isomers, Reaction Mechanism.

A stereoselective reaction is the one in which a reactant produces unequal mixture of isomers of expected product. In a stereoselective reaction, one isomer forms predominantly over other isomer. 

Apr 23, 2023

Racemic Mixture and Resolution of Racemic Mixture

In this article we will learn about what is Racemic mixture? and Resolution of racemic mixture.

Key words : Racemic Mixture, Enantiomer, Optical activity, Chirality.

A Racemic mixture or racemate is a combination of qual amount of enantiomers of chiral compound. The enantiomers are the type of isomers of chiral compound which are optical active, however racemic mixture is optically inactive

May 1, 2022

What is syn-anti isomerism?

Syn-anti isomerism in organic chemistry is a type of geometrical isomerism. The prefixes “syn” or “anti” are used to denote geometrical isomers
We have discussed geometrical isomerism in previous articles.1 Preferably, syn /anti notations are used for nomenclature of oximes that is aldoxime and ketoxime. Meaning of the word syn is “together” or “with”.  And meaning of the word anti is “opposite”. 

Apr 3, 2022

How to Calculate Enantiomeric Excess and Optical Purity?

Optical purity of compound is defined as percentage of major isomer present in the sample of compound.

Key words: Enantiomeric excess, Isomers, Enantiomers, optical purity

Mar 28, 2021

How to Write Newman Projection and Fischer Projection in Organic Chemistry

Newman projection  and Fischer projection formula are the way of writing structure of organic compounds to describe stereochemistry of molecule.

Key words: Newman projection, Fischer projectionStaggered conformer, Eclipsed conformer.

Mar 19, 2021

Conversion of Wedge Dash Projection to Newman Projection

In this article we will learn about conversion of Wedge dash projection to Newman projection of molecule in organic chemistry.
Wedge dash projection and Newman projection formula are the methods for representation three dimensional structure of molecule. 
Key words: Wedge dash structure, Newman projection.

Nov 2, 2020

Isomerism - Definitions, Type & Examples

Isomerism is the phenomenon in which two or more individual compounds have same molecular formula but different structures. Isomers are the compounds which have same molecular formula but they differ in the arrangement of atoms in the molecule. 

Key words: Isomerism, Structural Isomers, Chain Isomers, Position Isomers, Functional Group,  Isomers, Metamers, Tautomers, Ring Chain Isomers, Configurational Isomers, Enantiomers,  Stereoisomers, Conformational isomers, Diastereomers

Oct 2, 2020

Isomerism in Alkenes in Organic Chemistry

Isomers are the two individual compounds which have same molecular formula but they differ in the arrangement of atoms in the molecule.

Hi Friends, In this article we are going to learn about Isomerism in Alkenes in organic chemistry. .

Key words: Isomers, Structural isomers, Geometric isomers, Cis/trans isomersE / Z naming system

So what are isomers?

The word isomer is derived from Greek word “isomeros” where, iso means “equal” and meros means “part”.