Organic chemistry is a vast and complex field, forming the foundation for many scientific disciplines, including pharmaceuticals, biochemistry, and materials science. For graduate students, mastering key concepts in organic chemistry is essential for success in research and academia. Here are the top 10 organic chemistry concepts every graduate student must understand. (Figure 1)
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| Fig 1: Organic Chemistry Concepts |
Enamines,
play a crucial role in synthesizing a number of compounds with diverse
applications. In this blog post, we will dive into the fascinating world of
enamines, exploring their synthesis methods and reactions.
Key words: Enamine, Imine, Aldehyde, Ketone, Nucleophilic addition, Nucleophilic Substitution.
In this blog, we'll learn the chemistry behind acetal protection, exploring the synthesis methods that shield compounds and the subsequent hydrolysis processes that reveal their hidden potential.
In the vast realm of organic chemistry, the halogenation of alcohols stands out as a crucial technique for effecting functional group transformations. This powerful method allows chemists to modify the structure of organic compounds, providing a gateway to a diverse array of reactions and applications. In this comprehensive guide, we will delve into the intricacies of halogenation of alcohol, exploring the mechanisms, reaction conditions, and the broader implications of this transformative process.
Halogenation, Alkyl halide, Alcohol, Appel Reaction, Nucleophilic Substitution Reaction (SN1 & SN2)
In the intricate world of organic chemistry, where reactions and mechanisms govern the creation of countless compounds, the Wittig reaction or Wittig olefination stands as a powerful tool for the synthesis of alkenes from carbonyl compounds. Named after its inventor, German chemist Georg Wittig, this reaction has become a cornerstone in the repertoire of synthetic organic chemists. In this blog post, we will delve into the Wittig reaction, exploring its, mechanism, and applications.
High-Performance
Liquid Chromatography (HPLC) stands at the forefront of analytical techniques,
playing a pivotal role in various industries. From pharmaceuticals to
environmental analysis, HPLC's versatility makes it an indispensable tool for
scientists and researchers. In this article, we delve into the diverse
applications of HPLC, exploring its impact on drug development, environmental
safety, food quality, clinical research, and beyond.
Key words: High-performance liquid chromatography (HPLC), analytical technique, separation techniques,
In this blog we will learn about mutarotation. To understand the concept, it is important to understand related terminologies like Isomers, chirality, anomeric effect, and anomeric carbon. We have discussed these concepts in separate articles. Links are given below in reference section as well.
Key words: Mutarotation, Anomeric carbon, Anomeric effect, and Chirality.
In the vast realm of organic chemistry, certain reactions stand out for their intriguing mechanisms and transformative potential. One such reaction that has fascinated chemists for years is the Curtius Rearrangement. In this blog, we will embark on a journey through the intricate world of organic synthesis, delving into the depths of this rearrangement and understanding its underlying mechanism.
Key Words: Curtius Rearrangement, Acyl azide, Isocyanate, Organic Synthesis
In the realm of organic chemistry, the study of molecules extends beyond their chemical bonds and electronic properties. The three-dimensional arrangement of atoms within a molecule plays a significant role in determining its behavior and reactivity. This spatial consideration is known as "steric effects." In this blog, we will explore the concept of steric effects, its implications, and its importance in the world of chemistry.
The mesomeric effect, also known as resonance effect or conjugation effect, is a fundamental concept in organic chemistry. It plays a crucial role in understanding the behavior and reactivity of organic compounds. This article aims to provide a comprehensive overview of the mesomeric effect, its implications, and its significance in the field of organic chemistry.
Keywords: Pyrrole, Heterocycle, Aromatic Compounds, Pyrrole synthesis.
In this article we will learn about stereoselectivity. Here we will discuss significance of stereoselective reactions with examples.
Key words :Stereochemistry, Stereoselective Reaction, Isomers, Reaction Mechanism.
A stereoselective reaction is the one in which a reactant produces unequal mixture of isomers of expected product. In a stereoselective reaction, one isomer forms predominantly over other isomer.
In this article we will learn about Types of Pericyclic reactions. In organic chemistry, a pericyclic reaction is a chemical reaction where the reaction proceeds through concerted mechanism and it has cyclic transition state.
Keywords: Pericyclic Reaction, Electrocyclic reaction, Cycloaddition reaction,
Elimination reaction in organic chemistry has main types as E1-reaction, E2-reaction and E1cB-elimination reaction.
Key words: E1-reaction,
E2-reaction and E1cB-elimination reaction, Dehydrohalogenation, Dehalogenation,
Dehydration
Hi Friends, in this article we will learn elimination reactions in organic chemistry.
In this article we will discuss Imine compounds in chemistry. Here we will learn about formation, reactions, and mechanisms of imine compounds.
Imine is a chemical compound form as result of condensation of carbonyl compound (ketone or aldehyde) and amine.
In this article we will discuss about Grignard Reagents - Reactions, Mechanism, and Handling Procedures.
Grignard reaction is an organometallic chemical reaction. It was discovered by Victor Grignard and he was awarded the Nobel Prize (1912) in Chemistry for this work.
UV-Vis spectroscopy is a branch of spectroscopy is deals with absorption of light in ultraviolet and visible region.
Hi Friends, in this article we will learn about basics of UV visible spectroscopy and also see its applications in chemistry. Here we will discuss transition metal complexes and Beer-Lambert Law.
Keywords: UV-Vis spectroscopy, Coordination Complex, Beer-Lambert Law, P bond.
We have discussed various applications of spectroscopy in chemistry, medicine and environmental science in another article. Please check out for more details. [Link]
In this article we will learn about Reaction intermediates in chemistry. Here we will discuss Definition, Types, and Properties of reaction intermediates.
An intermediate species is certain unstable species formed in chemical reaction. They are highly reactive, unstable and often decomposes to neutral and stable species.
There are five types of intermediate found in chemistry namely; Radical, Carbocation, Carbanion, Carbene, Benzyne intermediates.
α-hydroxy ketones are important intermediates in organic synthesis. Various methods available for the synthesis of α-hydroxy ketones are described herein.
Dieckmann Condensation - Reaction, Mechanism, and Examples are described in this article.
Dieckmann condensation is a chemical reaction for the synthesis of cyclic β-keto esters. In this reaction diester reacts with base to produce cyclic β-keto esters. It is a Named reaction in organic chemistry.
Key words: Condensation, Cyclization reaction, β-keto esters, Named reaction.