Showing posts sorted by relevance for query organic synthesis. Sort by date Show all posts
Showing posts sorted by relevance for query organic synthesis. Sort by date Show all posts

Mar 25, 2025

Top 10 Organic Chemistry Concepts Every Graduate Student Must Master

Organic chemistry is a vast and complex field, forming the foundation for many scientific disciplines, including pharmaceuticals, biochemistry, and materials science. For graduate students, mastering key concepts in organic chemistry is essential for success in research and academia. Here are the top 10 organic chemistry concepts every graduate student must understand. (Figure 1)

Organic Chemistry Concepts
Fig 1: Organic Chemistry Concepts

Oct 22, 2023

Exploring the Curtius Rearrangement and Its Mechanism

In the vast realm of organic chemistry, certain reactions stand out for their intriguing mechanisms and transformative potential. One such reaction that has fascinated chemists for years is the Curtius Rearrangement. In this blog, we will embark on a journey through the intricate world of organic synthesis, delving into the depths of this rearrangement and understanding its underlying mechanism.

Key WordsCurtius Rearrangement, Acyl azide, IsocyanateOrganic Synthesis

Jul 5, 2023

Pyrrole: Exploring the Versatile Heterocyclic Compound

Introduction

Pyrrole is a fascinating heterocyclic compound that plays a crucial role in various fields, including chemistry, pharmaceuticals, and materials science. This article aims to delve into the structure, synthesis, and reactions of pyrrole, shedding light on its significance and applications.

Keywords: Pyrrole, Heterocycle, Aromatic Compounds, Pyrrole synthesis.

Nov 23, 2021

Synthesis of alpha-hydroxy ketones

α-hydroxy ketones are important intermediates in organic synthesis. Various methods available for the synthesis of α-hydroxy ketones are described herein.

Jan 26, 2024

Wittig Reaction Explained: Understanding the Mechanism and Applications in Organic Chemistry

In the intricate world of organic chemistry, where reactions and mechanisms govern the creation of countless compounds, the Wittig reaction or Wittig olefination stands as a powerful tool for the synthesis of alkenes from carbonyl compounds. Named after its inventor, German chemist Georg Wittig, this reaction has become a cornerstone in the repertoire of synthetic organic chemists. In this blog post, we will delve into the Wittig reaction, exploring its, mechanism, and applications.

Jul 29, 2023

Understanding Steric Effects: Impact on Molecular Structure and Reactivity

In the realm of organic chemistry, the study of molecules extends beyond their chemical bonds and electronic properties. The three-dimensional arrangement of atoms within a molecule plays a significant role in determining its behavior and reactivity. This spatial consideration is known as "steric effects." In this blog, we will explore the concept of steric effects, its implications, and its importance in the world of chemistry.

Feb 3, 2024

Mastering the Art of Acetal Protection: A Comprehensive Guide to Synthesis and Hydrolysis of Acetal

In this blog, we'll learn the chemistry behind acetal protection, exploring the synthesis methods that shield compounds and the subsequent hydrolysis processes that reveal their hidden potential.

Keywords: Acetal, Aldehyde, Ketone, Alcohols, Hydrolysis.

Aug 5, 2025

How Organic Chemistry Powers the Pharmaceutical Industry

Dear Friends in the blog we will explore how organic chemistry fuels the pharmaceutical industry from drug discovery to formulation and why it's essential for innovation and patient care. We will touch upon the important aspects of organic chemistry and pharmaceutical industry. 

Keywords: Pharmaceutical Industry, Active Pharmaceutical Ingredients (APIs), Structure Activity Relationship (SAR), Drug Design.

Feb 16, 2025

Organic Photochemistry: Key Concepts and Applications

Organic photochemistry is a fascinating field of study that explores the interaction of light with organic molecules, leading to chemical reactions. This branch of chemistry plays a pivotal role in advancing scientific knowledge and enabling innovations in various industries. In this blog, we will delve into the key concepts of organic photochemistry and highlight its practical applications, offering insights for graduate students and researchers.

Key words: Photochemistry, Jablonski Diagram, Quantum Yield, Photochemical Reactions.

May 25, 2021

Synthesis of Amines - Named Reactions and Mechanism

In this article we will learn about synthesis of amine compounds. We will discuss few Named reactions and mechanism.

Amines are the organic compounds and they are derivatives of ammonia. In this article we will discuss about various synthesis methods for preparation of amines. 

Key words: Amine, Organic Synthesis, Reactions of Amine, Name Reaction.

Apr 8, 2023

Types of Pericyclic Reactions

In this article we will learn about Types of Pericyclic reactionsIn organic chemistry, a pericyclic reaction is a chemical reaction where the reaction proceeds through concerted mechanism and it has cyclic transition state

KeywordsPericyclic ReactionElectrocyclic reactionCycloaddition reaction

Sigmatropic reaction.

Feb 26, 2024

A Comprehensive Guide to Enamine: Synthesis, Hydrolysis and Reactions

Enamines, play a crucial role in synthesizing a number of compounds with diverse applications. In this blog post, we will dive into the fascinating world of enamines, exploring their synthesis methods and reactions.

Key words: Enamine, Imine, Aldehyde, Ketone, Nucleophilic addition, Nucleophilic Substitution.

Jan 31, 2022

Imine - Formation, Reactions, and Mechanisms

In this article we will discuss Imine compounds in chemistry. Here we will learn about formation, reactions, and mechanisms of imine compounds.

Imine is a chemical compound form as result of condensation of carbonyl compound (ketone or aldehyde) and amine.

May 17, 2021

Synthesis of Alkyl Halides (Haloalkanes)

In this article we will learn about synthesis of Alkyl halides (Haloalkanes). 

Alkyl halides are the organic compounds which consists of halogen atom bonded to carbon atom. 

Key words: Alkyl halide, Haloalkane, Electrophilic addition, Radical substitution, Nucleophilic substitution.

May 1, 2021

Synthesis of Alkenes from Alkyl Halides

Alkene compounds are the hydrocarbons which consist of at least one carbon-carbon double bond. Various synthesis methods for the synthesis of alkene are described herein.

Sep 2, 2023

Reactions of Epoxides: Understanding Their Importance in Organic Chemistry

Epoxides, also known as oxiranes, are an intriguing class of organic compounds that play a pivotal role in various chemical reactions due to their unique three-membered ring structure. In this article, we'll delve into the diverse world of epoxide reactions, exploring their significance and applications within the realm of organic chemistry. 

Keywords: Epoxide, Nucleophilic AdditionGrignard Reaction, Halohydrin.

Jan 31, 2024

Halogenation of Alcohols: A Comprehensive Guide to the Functional Group Transformations

In the vast realm of organic chemistry, the halogenation of alcohols stands out as a crucial technique for effecting functional group transformations. This powerful method allows chemists to modify the structure of organic compounds, providing a gateway to a diverse array of reactions and applications. In this comprehensive guide, we will delve into the intricacies of halogenation of alcohol, exploring the mechanisms, reaction conditions, and the broader implications of this transformative process.

Keywords: 

Halogenation, Alkyl halide, Alcohol, Appel Reaction, Nucleophilic Substitution Reaction (SN1 & SN2)

May 21, 2023

Furan - Structure, Synthesis and Reactions

In this article we will learn about Furan. Here we will discuss structure, synthesis, its reactions and aromaticity of furan. 

Key words: Furan, Heterocyclic compound, Aromatic compoundHuckel rule.

Introduction

Furan is a five member oxygen atom containing heterocyclic compound. It is aromatic compound with the Chemical formula C4H4O and Molecular weight 68.08 g/mol. Furan is colorless volatile liquid with boiling point 31.3 °C. Furan is used as a key starting material for the synthesis of many important compounds.

Sep 23, 2020

Synthesis of Alcohols

In this article we will discuss about organic reactions which are commonly used for the Synthesis of Alcohols

Alcohols are the important intermediates in Organic Chemistry. They are widely used for synthesis of other functional groups such as alkyl halides, alkenes, ketones, aldehydes, carboxylic acids etc.

Key words: Alcohols, Nucleophilic SubstitutionHydration ReactionOxymercuration-demercurationHydroboration-oxidationDihydroxylation.

Jan 17, 2021

Reaction Yield - Definitions, Formula & Examples

In this article we will learn about Reaction Yield. The yield of reaction is the amount of product formed from given starting material. Reaction yield is written in percentage and given on the reaction arrow along with reaction conditions.

Key words: Chemical reaction, Theoretical yield, Percent yield, Overall yield.