Laboratory Techniques in Organic Chemistry

Laboratory Techniques in Organic Chemistry are some methods used to execute an experiment in lab. In organic chemistry lab various reactions or functional group transformations are performed by using numerous chemicals and instruments. 

How to Calculate Coupling Constant (J values) in Proton NMR Spectroscopy

Hi Friends, in this article we will see how to calculate coupling constants (J values) in ¹H-NMR Spectroscopy.

Key words: Coupling constant, Multiplicity, ¹H-NMR spectrum, Signal.

Definition of coupling constant

The coupling constant is a distance between sub-peaks expressed in hertz. In ¹H-NMR spectrum a peak splits into multiple sub-peaks due to coupling with neighboring protons. The value of the coupling constant does not depend upon the frequency of the machine and solvent used for the NMR experiment.

We have discussed various applications of spectroscopy in chemistry, medicine, and environmental science in another article. Please check out for more details. [Link]

Purification of Organic Compounds

Purification of organic compounds can be accomplished using a variety of approaches. There are techniques or methods used by organic chemists to purify chemical compounds in laboratory. 

Key words: Purification, Organic compounds, Chromatography, Crystallization.

Dieckmann Condensation - Reaction, Mechanism, and Examples

Dieckmann Condensation - Reaction, Mechanism, and Examples are described in this article.

Dieckmann condensation is a chemical reaction for the synthesis of cyclic β-keto esters. In this reaction diester reacts with base to produce cyclic β-keto esters. It is a Named reaction in organic chemistry.

Key words: Condensation, Cyclization reaction, β-keto esters, Named reaction.

Claisen Condensation - Reaction, Mechanism, and Examples

Claisen condensation - Reaction, Mechanism, and Examples are described in this article.

Claisen condensation is a chemical reaction is used for the synthesis of β-keto esters. It is a Named reaction in organic chemistry. It is C-C coupling reaction in organic chemistry. 

Key words: Coupling reaction, Ester, β-keto ester, Name reaction.